Call for Chapters: Examining Biological Relevance of Fused S-Heterocycles

Editors

Shrikaant Kulkarni, Adjunct Professor, Faculty of Business, Victorian Institute of Technology, Melbourne, India
Hemantkumar Akolkar, Head and Assistant Professor, Rayat Shikshan Sanstha’s Abasaheb Marathe Arts and New Commerce, Science College, Rajapur, Dist- Ratnagiri., India
Vijay Khedkar, Associate Professor, Department of Pharmacy, Vishwakarma University, Pune, Maharashtra, India, India
Nirmala Darekar, Assistant Professor, Department of Chemistry, Rayat Shikshan Sanstha’s Radhabai Kale Mahila Mahavidyalaya, Ahmednagar, Maharashtra, India, 414001, India

Call for Chapters

Proposals Submission Deadline: July 7, 2024
Full Chapters Due: September 8, 2024
Submission Date: September 8, 2024

Introduction

In the realm of organic chemistry, fused s-heterocycles stand as captivating structures, possessing a unique amalgamation of atoms that spark curiosity among chemists and biologists alike. These compounds, characterized by their fused ring systems containing sulfur atoms, have garnered attention for their diverse chemical properties and their potential biological activities. This book embarks on a journey to unravel the biological relevance of fused s-heterocycles, examining their interactions within biological systems and elucidating their potential applications in medicine, agriculture, and beyond. Through a comprehensive exploration of their synthesis, structure-activity relationships, and mechanisms of action, we aim to shed light on the pivotal role these molecules play in nature and in the laboratory. Fused s-heterocycles exhibit a remarkable ability to modulate biological processes, ranging from enzyme inhibition to cellular signaling. Their structural diversity allows for fine-tuning of biological activity, making them promising candidates for drug discovery and development. Furthermore, their natural occurrence in bioactive compounds underscores their importance as privileged scaffolds in medicinal chemistry. In this book, we will navigate through the synthesis strategies employed to access fused s-heterocycles, discussing both classical and modern synthetic methodologies. We will also delve into their spectroscopic properties and computational studies, providing insights into their molecular behavior and reactivity. Additionally, we will explore case studies and recent advancements in the field, highlighting key examples of fused s-heterocycles with significant biological activities. From antiviral agents to anticancer compounds, these molecules showcase the breadth of their therapeutic potential and inspire further exploration into their pharmacological properties. Through the interdisciplinary lens of chemistry and biology, this book seeks to bridge the gap between synthetic chemistry and biological sciences, fostering a deeper understanding of the biological relevance of fused s-heterocycles. By elucidating their mechanisms of action and biological targets, we aim to pave the way for the rational design of novel bioactive compounds with enhanced efficacy and selectivity. Join us on this captivating journey as we unravel the intricate relationship between fused s-heterocycles and the biological world, uncovering the hidden potential of these fascinating molecules. This introduction sets the stage for a comprehensive exploration of fused s-heterocycles, touching upon their synthesis, biological activities, and potential applications.

Objective

The objective of the book is to provide a thorough examination of the biological relevance of fused s-heterocycles, aiming to uncover their potential applications in various fields such as medicine and agriculture. The key objectives outlined in the introduction include: Exploration of Biological Interactions: The book seeks to delve into the interactions of fused s-heterocycles within biological systems, shedding light on how these compounds modulate various biological processes. Synthesis and Structure-Activity Relationships: Through a comprehensive exploration, the book aims to discuss the synthesis strategies employed to access fused s-heterocycles, as well as elucidate the structure-activity relationships governing their biological activities. Mechanisms of Action: By examining the mechanisms of action of fused s-heterocycles, the book intends to provide insights into how these molecules exert their effects on biological targets, ranging from enzyme inhibition to cellular signaling. Potential Applications: The book highlights the potential applications of fused s-heterocycles in drug discovery and development, showcasing their versatility as promising candidates for the treatment of various diseases. Interdisciplinary Approach: By bridging the gap between synthetic chemistry and biological sciences, the book aims to foster a deeper understanding of the biological relevance of fused s-heterocycles, facilitating the rational design of novel bioactive compounds with enhanced efficacy and selectivity. Overall, the objective of the book is to unravel the intricate relationship between fused s-heterocycles and the biological world, uncovering their hidden potential and inspiring further exploration into their pharmacological properties.

Target Audience

Chemists and Organic Chemists: Researchers and practitioners in the field of organic chemistry who are interested in the synthesis, structure, and properties of fused s-heterocycles. Medicinal Chemists: Professionals involved in drug discovery and development, seeking to explore the potential of fused s-heterocycles as novel therapeutic agents. Biochemists and Molecular Biologists: Individuals studying biological systems and molecular interactions, interested in understanding the mechanisms of action of fused s-heterocycles within living organisms. Pharmacologists and Pharmaceutical Scientists: Experts in pharmacology and pharmaceutical sciences who aim to explore the pharmacological properties and potential applications of fused s-heterocycles in medicine. Students and Academics: Undergraduate and graduate students, as well as academic researchers, interested in gaining a deeper understanding of the biological relevance and synthetic methodologies of fused s-heterocycles. Industrial Researchers: Professionals working in industries such as pharmaceuticals, agrochemicals, and biotechnology, seeking to explore the practical applications of fused s-heterocycles in their respective fields. Educators and Instructors: Teachers and educators in chemistry and related disciplines who may use the book as a reference or textbook for courses on organic chemistry, medicinal chemistry, or chemical biology. Overall, the book caters to a multidisciplinary audience with varying levels of expertise, providing valuable insights into the biological significance and potential applications of fused s-heterocycles.

Recommended Topics

Chapter 1: Introduction to Fused S-Heterocycles Overview of fused s-heterocycles Historical perspective Importance in organic chemistry and biology Chapter 2: Synthesis Strategies Classical methods for the synthesis of fused s-heterocycles Modern synthetic approaches Green chemistry methodologies Chapter 3: Structural Diversity and Characterization Structural motifs and diversity Spectroscopic techniques for characterization Computational methods for structural prediction Chapter 4: Biological Targets and Interactions Enzyme inhibition studies Receptor binding assays Cellular uptake and distribution Chapter 5: Mechanisms of Action Signaling pathways modulation DNA and RNA interactions Protein-protein interactions Chapter 6: Structure-Activity Relationships (SAR) SAR studies in drug design Quantitative structure-activity relationships (QSAR) Pharmacophore modeling Chapter 7: Antiviral Agents Discovery and development of antiviral compounds Mechanisms of antiviral action Case studies of potent antiviral agents Chapter 8: Anticancer Compounds Design and synthesis of anticancer agents Cellular targets and pathways Preclinical and clinical studies Chapter 9: Neurological Agents Neurotransmitter modulation Neuroprotective compounds Treatment of neurological disorders Chapter 10: Agricultural Applications Herbicides and weed control Insecticides and pest management Crop protection and enhancement Chapter 11: Environmental Remediation Pollutant degradation mechanisms Water and soil remediation techniques Sustainable approaches to environmental cleanup Chapter 12: Bioavailability and Pharmacokinetics Absorption, distribution, metabolism, and excretion (ADME) Formulation strategies for improved bioavailability Pharmacokinetic modeling and simulations Chapter 13: Toxicology and Safety Assessment Assessment of acute and chronic toxicity In vitro and in vivo toxicity testing Risk assessment and regulatory considerations Chapter 14: Future Perspectives Emerging trends in fused s-heterocycle research Opportunities for interdisciplinary collaboration Challenges and obstacles to overcome Chapter 15: Conclusion and Outlook Summary of key findings Potential impact on science and society Future directions for research and application Examples 1) Imidazothiazole 2) Imidazolothiadiazole 3) Thiazolothiadiazole 4) Pyrazolothiazole 5) Thiazolotriazoles 6) Thienopyrrole 7) Triazolothiadiazole 8) Thiazolopyridines 0) Thienopyrimidine 10) Thiazolopyrimidines 11)Tetrazoloquinoline

Submission Procedure

Researchers and practitioners are invited to submit on or before July 7, 2024, a chapter proposal of 1,000 to 2,000 words clearly explaining the mission and concerns of his or her proposed chapter. Authors will be notified by July 21, 2024 about the status of their proposals and sent chapter guidelines.Full chapters are expected to be submitted by September 8, 2024, and all interested authors must consult the guidelines for manuscript submissions at https://www.igi-global.com/publish/contributor-resources/before-you-write/ prior to submission. All submitted chapters will be reviewed on a double-anonymized review basis. Contributors may also be requested to serve as reviewers for this project.

Note: There are no submission or acceptance fees for manuscripts submitted to this book publication, Examining Biological Relevance of Fused S-Heterocycles. All manuscripts are accepted based on a double-anonymized peer review editorial process.

All proposals should be submitted through the eEditorial Discovery® online submission manager.



Publisher

This book is scheduled to be published by IGI Global (formerly Idea Group Inc.), an international academic publisher of the "Information Science Reference" (formerly Idea Group Reference), "Medical Information Science Reference," "Business Science Reference," and "Engineering Science Reference" imprints. IGI Global specializes in publishing reference books, scholarly journals, and electronic databases featuring academic research on a variety of innovative topic areas including, but not limited to, education, social science, medicine and healthcare, business and management, information science and technology, engineering, public administration, library and information science, media and communication studies, and environmental science. For additional information regarding the publisher, please visit https://www.igi-global.com. This publication is anticipated to be released in 2025.



Important Dates

July 7, 2024: Proposal Submission Deadline
July 21, 2024: Notification of Acceptance
September 8, 2024: Full Chapter Submission
October 13, 2024: Review Results Returned
November 10, 2024: Final Acceptance Notification
November 17, 2024: Final Chapter Submission



Inquiries

Shrikaant Kulkarni Adjunct Professor, Faculty of Business, Victorian Institute of Technology, Melbourne shrikaant.kulkarni@vit.edu.au Hemantkumar Akolkar Head and Assistant Professor, Rayat Shikshan Sanstha’s Abasaheb Marathe Arts and New Commerce, Science College, Rajapur, Dist- Ratnagiri. hemantakolkar@gmail.com Vijay Khedkar Associate Professor, Department of Pharmacy, Vishwakarma University, Pune, Maharashtra, India vijaycpn@gmail.com Nirmala Darekar Assistant Professor, Department of Chemistry, Rayat Shikshan Sanstha’s Radhabai Kale Mahila Mahavidyalaya, Ahmednagar, Maharashtra, India, 414001 darekarnirmala111@rediffmail.com

Classifications


Life Sciences; Physical Sciences and Engineering
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