Call for Chapters: Five Membered Bioactive N and O-Heterocycles: Models and Medical Applications

Editors

Shrikaant Kulkarni, Adjunct Professor, Faculty of Business, Victorian Institute of Technology, Melbourne, India
Hemantkumar Akolkar, Head and Assistant Professor, Rayat Shikshan Sanstha’s Abasaheb Marathe Arts and New Commerce, Science College, Rajapur, Dist- Ratnagiri., India
Bapurao Shingate, Assistant Professor, Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad-431 004, Maharashtra (INDIA), India
Vijay Khedkar, Associate Professor, Department of Pharmacy, Vishwakarma University, Pune, Maharashtra, India, India

Call for Chapters

Proposals Submission Deadline: June 23, 2024
Full Chapters Due: August 25, 2024
Submission Date: August 25, 2024

Introduction

This book explores the comprehensive review of syntheses and pharmaceutical applications of five-membered bioactive heterocycles containing two or more heteroatoms. This book will help medicinal chemists to develop a new synthetic methodology that enables quick access to a wide range of functionalized heterocyclic compounds. Heterocyclic compounds are a class of organic compounds that contain at least one atom other than carbon in the ring structure. The presence of heteroatoms such as nitrogen, oxygen, and sulfur in the aromatic ring increases the polarity and offers the possibility of hydrogen bonds that can improve the binding affinity and selectivity of the drug at the target site. Heteroaromatic rings are considered preferred structures due to their ability to replace common motives in medicinal chemistry, enabling an improvement of metabolic stability, solubility, and bioavailability, which are essential elements for the development of effective drugs. These properties can lead to the modulation of different biochemical metabolic pathways, resulting in therapeutic effects. Among active compounds with aromatic groups, five-membered heterocyclic compounds are of great importance in the field of pharmaceutical and medicinal chemistry. These rings belong to a class of organic compounds that contain at least one non-carbon atom within their structure. The various synthetic protocols like microwave-assisted, nano-catalyzed, green synthesis, click reaction, and multicomponent routes could be used for the betterment of the purity of products, selectivity, and yields of the products. The inclusion of heteroatoms such as nitrogen, oxygen, and sulfur in the aromatic ring enhances the polarity of the compound and introduces the potential for multiple target-inhibitor interactions. This, in turn, improves the drug’s binding affinity and selectivity at the intended target site. Heteroaromatic rings are considered favorable structures in medicinal chemistry as they can replace common motifs, leading to enhanced metabolic stability, solubility, and bioavailability. Due to their unique physicochemical properties and biological effects, these compounds are used as key structural motifs in many clinically effective drugs. Therefore, the development and synthesis of novel five-membered heterocycles remains an important research area in medicinal chemistry, to find new drugs for the treatment of various diseases. In overall, this book will provide a current update on bioactive five-membered heterocycles, showing that these molecules can serve as a guiding reservoir for researchers in nearly every pathological condition, assisting them in the creation of new and effective lead compounds.

Objective

to use it as a reference book by academicians, research scholars, and the scientific community who are endeavoring to design &develop novel five-membered heterocycles containing bioactive molecules. to present an overview of the applications of synthetic protocols for the preparation of five-membered heterocyclic compounds containing two or more heteroatoms (O, N, S) at different-different positions along with their different potent and competent candidates against various diseases. To present a comprehensive review on five-membered bioactive heterocycles: Synthesis and biological applications. To evolvie at new, green, and sustainable method protocols for five-membered heterocycles with two or more heteroatoms. To provide recent biological applications of five-membered bioactive heterocycles. To give insight about current trends in five-membered heterocycles with two or more heteroatoms.

Target Audience

Professors/Lecturers who are teaching courses related to Heterocyclic chemistry. Researchers in the area of Heterocyclic chemistry Students in the field of Heterocyclic chemistry College libraries and book stores Research centers and Institutes & Industries

Recommended Topics

Section I: Bioactive five-membered heterocycles with two heteroatoms 1) 1,3-Oxazole 2) Pyrazole 3) Imidazole Section II: Bioactive five-membered heterocycles with three heteroatoms 4) 1,2,3-Triazole 5) 1,2,4-Triazole 6) 1,2,4-Oxadiazole 7) 1,3,4-Oxadiazole Section III: Bioactive five-membered heterocycles with two heteroatoms fused with a benzene ring 8) Indazole 9) Benzimidazole 10) Benzoxazole 11) Benzotriazole Section IV: Topics other than above but within the ambit of book theme

Submission Procedure

Researchers and practitioners are invited to submit on or before June 23, 2024, a chapter proposal of 1,000 to 2,000 words clearly explaining the mission and concerns of his or her proposed chapter. Authors will be notified by July 7, 2024 about the status of their proposals and sent chapter guidelines.Full chapters are expected to be submitted by August 25, 2024, and all interested authors must consult the guidelines for manuscript submissions at https://www.igi-global.com/publish/contributor-resources/before-you-write/ prior to submission. All submitted chapters will be reviewed on a double-anonymized review basis. Contributors may also be requested to serve as reviewers for this project.

Note: There are no submission or acceptance fees for manuscripts submitted to this book publication, Five Membered Bioactive N and O-Heterocycles: Models and Medical Applications. All manuscripts are accepted based on a double-anonymized peer review editorial process.

All proposals should be submitted through the eEditorial Discovery® online submission manager.



Publisher

This book is scheduled to be published by IGI Global (formerly Idea Group Inc.), an international academic publisher of the "Information Science Reference" (formerly Idea Group Reference), "Medical Information Science Reference," "Business Science Reference," and "Engineering Science Reference" imprints. IGI Global specializes in publishing reference books, scholarly journals, and electronic databases featuring academic research on a variety of innovative topic areas including, but not limited to, education, social science, medicine and healthcare, business and management, information science and technology, engineering, public administration, library and information science, media and communication studies, and environmental science. For additional information regarding the publisher, please visit https://www.igi-global.com. This publication is anticipated to be released in 2025.



Important Dates

June 23, 2024: Proposal Submission Deadline
July 7, 2024: Notification of Acceptance
August 25, 2024: Full Chapter Submission
September 29, 2024: Review Results Returned
October 27, 2024: Final Acceptance Notification
November 3, 2024: Final Chapter Submission



Inquiries

Shrikaant Kulkarni
Adjunct Professor, Faculty of Business, Victorian Institute of Technology, Melbourne
shrikaant.kulkarni@vit.edu.au

Hemantkumar Akolkar
Head and Assistant Professor, Rayat Shikshan Sanstha’s Abasaheb Marathe Arts and New Commerce, Science College, Rajapur, Dist- Ratnagiri.
hemantakolkar@gmail.com

Bapurao Shingate
Assistant Professor, Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad-431 004, Maharashtra (INDIA)
bapushingate@gmail.com

Vijay Khedkar
Associate Professor, Department of Pharmacy, Vishwakarma University, Pune, Maharashtra, India
vijaycpn@gmail.com



Classifications


Life Sciences; Medicine and Healthcare; Physical Sciences and Engineering
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